In silico antibody accessibility analysis indicates that ectodomain epitopes are transiently exposed, while MPER epitopes are virtually always occluded in the pre-fusion trimer.

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

Whereas most prokaryotes rely on binary fission for propagation, many species use alternative mechanisms, which include multiple offspring formation and budding, to reproduce. In some bacterial ...

The term pharmacogenomics, which first appeared in the literature in 1997 (Ref. 1), is often described as the whole-genome application of pharmacogenetics, and there is a large overlap between these ...

For decades, geneticists have known that most common illnesses are not caused by a single rogue gene but by intricate constellations of DNA variants acting together in specific cells. Now a new ...

Until she was thirty-three, Kathryn Paige Harden, a professor of psychology at the University of Texas at Austin, had enjoyed a vocational ascent so steady that it seemed guided by the hand of ...

Christmas has come and gone, but most of us luckily still have this weekend to recover before heading back to work on Monday. If you want to keep the holiday spirit rolling, Netflix is jam-packed with ...

(BPT) - Like every year, many of us make New Year's resolutions and try to stick to them, but broad, all-or-nothing changes often set us up for failure and can make mental health struggles even worse.