A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as ...

CDT1 inhibits the helicase activity of the MCM complex, thereby suppressing nascent strand synthesis in DNA replication in cultured human cells. This action results in fork collapse and DNA damage, ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

Objectives Understanding the molecular changes in the preclinical synovium is crucial for identifying factors that drive arthritis development. Persistent DNA damage in tissues is known to drive a ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic tangles overwhelm normal repair pathways, cells flip on a fast but error-prone ...

Scientists have captured the first detailed 'molecular movie' showing DNA being unzipped at the atomic level -- revealing how cells begin the crucial process of copying their genetic material.

Franklin W. Stahl, an American molecular biologist whose landmark 1957-58 experiment with colleague Matthew Meselson revealed how DNA replicates, helping pave the way for a revolution in genetics ...

A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as a kind of "traffic controller" on DNA. Without this protein, chaos ensues, ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...