This important study, which tackles the challenge of analyzing genome integrity and instability in unicellular pathogens by introducing a novel single-cell genomics approach, presents compelling ...

Pioneering research utilizes high-throughput single-cell sequencing to demystify the microbial universe within activated sludge, a cornerstone of wastewater treatment. This study has unearthed a ...

The human gut microbiome is complex and diverse, with significant implications for health and disease. The study develops smRandom-seq2, a droplet-based method that overcomes the limitations of ...

The landscape of next-generation sequencing (NGS) continues to be defined by astonishing technological progress. We continue ...

Misfolded proteins can appear as small aggregates, soluble monomers, or large insoluble inclusion bodies. While the fundamental biophysical mechanisms that cause cytotoxicity are not fully understood, ...

The human gut microbiome is complex and diverse, with significant implications for health and disease. The study develops ...

This image illustrates the typical steps in next-generation sequencing (excluding single-molecule sequencing methods). The process begins with isolating genomic DNA (a) and breaking it into short ...

The low-pass whole genome sequencing technique involves sequencing each genome base several times. It is increasingly popular in agricultural studies, as agricultural genomes typically have a broader ...

Preliminary results from a first-in-human trial of AMT-116, a topoisomerase I inhibitor containing antibody-drug conjugate (ADC), in patients with advanced solid tumors. A novel oral microtubule ...

One-step Library Prep Workflow Designed to Address the Scalability, Performance, and Affordability Needs of Applied ...