DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave. Researchers have now mapped this hidden architecture in unprecedented detail, showing ...
A research team led by Zhiping Weng, Ph.D., and Jill Moore, Ph.D."18, at UMass Chan Medical School, has nearly tripled the ...
We propose to generate high-density whole genome maps in nano-channels by combining Cas9- guide-RNA (gRNA) sequence-specific DNA labeling and motif-based DNA labeling. Cas9-guide- RNA (gRNA) DNA ...
The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...
The Human Genome Project changed everything. A map of the entire human sequence of DNA was the starting point for an enormous number of discoveries, from disease genes to how humans evolved. But DNA ...
Roland Siezen and colleagues at the University of Nijmegen, the Netherlands, have created a software tool that's long overdue. Most researchers in the eukaryotic model organism community have genome ...
In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...
Scientists created the largest functional map of a brain to date using a piece of a mouse's brain. The map details the wiring that connects neurons, offering insight into brain function and ...
Passing yet another milestone in the rapidly advancing science of genetics, biologists said yesterday that they had compiled a map of the hereditary instructions of the laboratory mouse, the single ...
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