Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...
Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA ...
Tardigrades were first discovered in the Eighteenth Century and are known to survive in some of Earth’s most inhospitable environments. “What we saw surprised us,” study co-author and University of ...
Changes in genes have been linked to the development of different diseases for a while. However, it's not exactly clear what ...
Scientists have developed a new CRISPR-based technology that could offer a safer approach to correcting genetic defects. The new 'soft' CRISPR approach makes use of natural DNA repair machinery, ...
Bacteria and mammals may use similar mechanisms in a major yet poorly understood DNA repair pathway, suggests a report in the October 22 Science. In theory, coauthor Aidan Doherty of the University of ...
ANN ARBOR--Proteins inside bacteria cells engage in "search-and-rescue"-type behavior to ferret out mismatched DNA and fix it to thwart dangerous mutations that can be associated with certain cancers, ...
When a long-term memory forms, some brain cells experience a rush of electrical activity so strong that it snaps their DNA. Then, an inflammatory response kicks in, repairing this damage and helping ...
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